416 customer reviews
60 Vegetable Capsules
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Product Details

PreToxx helps reduce hangover symptoms and supports liver function. Natural ingredients including prickly pear and milk thistle extracts work while you drink, helping to metabolize the toxins that cause hangover symptoms and to support a healthy liver. PreToxx capsules now include a powerful electrolyte blend to help replenish vital nutrients lost during alcohol consumption.*

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Supplement Facts
Serving Size: 3 V-Capsules
Servings Per Container: 20
% Daily Value
Amount Per Serving
450 mg
Vitamin C (ascorbic acid)
105 mg
Vitamin B-1 (thiamin HCl)
48 mg
Vitamin B-6 (pyridoxine HCl)
240 mcg
Vitamin B-12 (cyanocobalamin)
48 mg
Calcium (amino acid chelate)
24 mg
Magnesium (amino acid chelate)
1560 mcg
Manganese (amino acid chelate)
60 mg
Chloride (sodium chloride)
35 mg
Sodium (sodium chloride)
24 mg
Potassium (amino acid chelate)
1110 mg
Liver Antioxidant Blend
N-Acetyl L-Cysteine (NAC), Prickly Pear Extract (NOPAL), Milk Thistle Extract
** Daily Value not established
Other Ingredients: Microcrystalline Cellulose, Rice Flour, Magnesium Stearate, Silicon Dioxide


  • N-Acetyl-L-Cysteine - NAC is a powerful antioxidant that helps boost your body's stores of glutathione, your liver's detoxifier that assists in breaking down alcohol.*
  • Prickly Pear Extract - Prickly pear extract has been shown in studies to help relieve symptoms of nausea, dry mouth, and loss of appetite.*
  • Milk Thistle - Milk thistle has been shown to protect the liver from toxins and to support its healthy function.*
  • B-Vitamins - Infused with B1 (Thiamine), B6, and B12. These water-soluble vitamins are important in metabolic processes and can be depleted during heavy alcohol consumption.*
  • Electrolyte Blend - A unique blend of calcium, magnesium, sodium chloride, potassium and manganese that replenishes the body with vital electrolytes lost during alcohol consumption.*


Take three (3) capsules before drinking with a glass of water. Repeat after drinking. To help support a healthy liver, take one (1) capsule daily.*

PreToxx will not prevent or affect alcohol intoxication. Inform your physician if you are being treated for any medical condition or are nursing. Keep out of reach of children. Do not drink and drive.

Reviews (416)

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Works well. by Storestoofar on Mar 4, 2015 (Source: Amazon)

Worked for me multiple times. Imagine an all inclusive vacation....champagne brunch, frozen pool drinks, afternoon nap with beers, pre-dinner cocktails, wine with dinner (and the occasional tequila or sake shot), brandy night caps. Yep. This helped.

It's worth trying... by DayLateDollarShort on Feb 25, 2015 (Source: Amazon)

First off it does work (and I am a VERY skeptical person), and when used as directed it works VERY well.

Here are a few key points I've discovered (so far I have tried this product about 10 times).

1) They don't work the same on everybody. I think people that get depleted bad of vitamin B complex when drinking will have the greatest benefit, but not everyone is the same. I personally think hangovers have different causes for everyone. It worked great for me, but my other friends said it worked "good" or "ok" but not "amazing". If all the other test subjects I've given this product too however, nobody reported this as "bogus" and all said they would rather have it than not. If you already have a strong B complex diet you might not see much benefit. However it's rare for Americans to have a strong B complex diet so you should see some benefit.

2) I don't have the headache or anxiety from a hangover when using this, but I do feel tired (just as you would with a hangover) and I do have "rotgut". However for me that's a great tradeoff. I got REALLY bad headaches and the anxiety/depression drove me crazy.

3) It has a "tolerance" too. The first time I took this I got the best results. The first time I took this I felt like I cheated death and was invincible. The times after have still been good, but not like the first time. It does not seem to work consecutively either. If you're going to drink Friday and Saturday night, don't expect to be invincible the whole weekend. In those situations, I will take it Friday and just go easy on Saturday.

4) It does have a disgusting taste, but who cares.

Can't go wrong if you have horrible hangovers! by Janis E. Mousa on Feb 24, 2015 (Source: Amazon)

IT really worked! I took as directed on back of bottle and I woke up the feeling as I did in my teens and 20's!

Five Stars by Long Z. on Feb 23, 2015 (Source: Amazon)


This stuff works! by John B. on Feb 22, 2015 (Source: Amazon)

These pills really do reduce hangover woes. I'm 51 years old, with plenty of experience dealing with hangovers, but in the past few years I was finding that even having just a few beers would give me a nasty hangover. After reading the Amazon reviews on PreToxx, I was hoping it would work as advertised, and I'm very pleased to report it does. I take 2 pills before drinking and 2 pills after drinking, and in the morning I feel pretty decent, way better than I had been. If I had a lot to drink, I'll still feel kind of dazed and tired in the morning, but no headache, no real illness. I'm a research chemist, and I've read up on digestion and metabolism of alcohol, and it basically occurs in 2 steps -- conversion of the ethanol to acetaldehyde, then conversion of acetaldehyde to acetic acid. It's the acetaldehyde that is mostly responsible for nasty hangover effects, so if your body's enzymes aren't doing their job to convert the acetaldehyde quickly, you gonna feel like crap. My guess is that PreToxx is helping to speed along the acetaldehyde conversion.

But whatever the mechanism, it's working for me. After a couple weekends using it with good results, I bought 3 more bottles.

No more Nausea! by Andres A Gonzalez on Feb 22, 2015 (Source: Amazon)

I cannot believe these actually works! I was very hesitant on purchasing these but after reading all the reviews I figured I'd give em a shot. Going into my thirties I just cannot tolerate hangovers as gracefully as i did in my 20's. Recovering from those usually put me out of commission for a day or two. Not with ProToxx. As long as you follow the instructions and keep hydrated ,hangovers will be a thing of the past.

Awesome product. It obviously isn't a magical cure but ... by Mary on Feb 20, 2015 (Source: Amazon)

Awesome product. It obviously isn't a magical cure but it does SUBSTANTIALLY cut down on my hangovers. Every time I take this I am so happy I did! I order them 2 at a time now as all of my friends always want some too and now buy it as well.

This stuff really works! by Ken Nothnagel on Feb 20, 2015 (Source: Amazon)

This stuff really works!

Four Stars by David on Feb 17, 2015 (Source: Amazon)

Would recomend PreToxx.

skeptic turned believer by kamalei on Feb 16, 2015 (Source: Amazon)

I was a little skeptical at first. I've tried other brands and had very appeasing results however those brands are either out of stock or just not available on amazon. On a whim, I decided to try pretoxx. What drew me to the product was the fact that the ingredients were all ones that I could read in plain english and didn't have to look up in a dictionary. I liked the "naturalness" of the product and haven't been disappointed yet. I'm almost through my first bottle and every time I use the product, I have not woken up with the throbbing headache, "hollow head" or general overall yuckiness that accompanies drinking an entire bottle of not-so-expensive chardonnay or pinot noir that I tend to indulge in weekly (and trust me, sometimes, I'm trying to push the envelope). I am definitely sold but you should give it a try yourself.

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